let-7d-3p is associated with apoptosis and response to neoadjuvant chemotherapy in ovarian cancer
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چکیده
منابع مشابه
Response to neoadjuvant chemotherapy in locally advanced gastric and gastroesophageal cancer: Phase II clinical trial
Background: Gastric cancer is an important health problem across the world. Chemotherapy in combination with local treatment is standard treatment for locally advanced gastroesophageal cancers. The purpose of this investigation was evaluation of response and tolerability to neoadjuvant EOX regimen in locoregionally advanced gastric cancer. Materials and Methods: patients with locoregionally adv...
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Objectives: Multidrug resistance (MDR), which may be due to the over expression of P-glycoprotein (Pgp) and/or MRP, is a major problem in neoadjuvant chemotherapy of osteosarcoma. The aim of this study was to investigate the role of Tc-99m MIBI scan for predicting the response to pre-operative chemotherapy. Materials and Methods: Twenty-five patients (12 males and 13 females, aged between 8 and...
متن کاملDecreased expression of let-7c is associated with non-response of muscle-invasive bladder cancer patients to neoadjuvant chemotherapy
The identification and development of biomarkers which predict response of muscle invasive bladder cancer (MIBC) patients to neoadjuvant chemotherapy would likely increase usage of this treatment option and thereby improve patient survival rates. MiRNA array and qRT-PCR validation was used to identify miRNA which are associated with response to neoadjuvant chemotherapy. RNA was extracted from a...
متن کاملNeoadjuvant Chemotherapy in Ovarian Cancer
Objective: The primary objective of the study was to compare the efficacy and safety of adjuvant chemotherapy (ACT) with neoadjuvant chemotherapy (NACT) in patients with ovarian epithelial cancer (OEC). Place & Duration of Study: This Randomized Controlled Trial was conducted at Shaukat Khanum Memorial Cancer Hospital & Research Center, Lahore (Pakistan). Patients were enrolled and treated over...
متن کاملRB-pathway disruption is associated with improved response to neoadjuvant chemotherapy in breast cancer.
PURPOSE We sought to determine whether dysregulation of the retinoblastoma (RB) tumor suppressor pathway was associated with improved response to neoadjuvant chemotherapy in breast cancer. EXPERIMENTAL DESIGN An RB-loss signature was used to analyze the association between pathway status and pathologic complete response in gene expression datasets encompassing three different neoadjuvant regi...
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ژورنال
عنوان ژورنال: Oncology Reports
سال: 2018
ISSN: 1021-335X,1791-2431
DOI: 10.3892/or.2018.6366